Search results for " campthotecin"

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Hybrid supramolecular gels of Fmoc-F/halloysite nanotubes: Systems for sustained release of camptothecin

2017

Supramolecular gel hybrids obtained by self-assembly of Fmoc-L-phenylalanine (Fmoc-F) in the presence of functionalized halloysite nanotubes (f-HNT) were obtained in biocompatible solvents and employed as carriers for the delivery of camptothecin (CPT) molecules. The synthesis of the new f-HNT material as well as its characterization are described. The properties of the hybrid hydrogels and organogels were analyzed by several techniques. The presence of small amounts of f-HNT allows good dispersion of the tubes and the subsequent formation of homogeneous gels. The experimental results show that f-HNT functions only as an additive in the hybrid gels and does not demonstrate gelator behavior.…

Materials scienceSupramolecular chemistryBiomedical EngineeringNanotechnology02 engineering and technologyengineering.material010402 general chemistry01 natural sciencesHalloysiteChemistry (all); Biomedical Engineering; Materials Science (all)HeLamedicineMoleculeGeneral Materials Sciencehalloysite supramolecular gel campthotecin drug delivery rheological propertiesSettore CHIM/02 - Chimica FisicabiologyChemistry (all)Settore CHIM/06 - Chimica OrganicaGeneral ChemistryGeneral Medicine021001 nanoscience & nanotechnologybiology.organism_classification0104 chemical sciencesSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiChemical engineeringSelf-healing hydrogelsengineeringMaterials Science (all)Nanocarriers0210 nano-technologyDrug carrierCamptothecinmedicine.drug
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